Analysis of the therapeutic effects of mechanical ventilation with different tidal volume on the children with severe pneumonia.

Objective To observe the therapeutic effects of mechanical ventilation with different tidal volume on the children with severe pneumonia.Methods Fifty child patients with severe pneumonia were given mechanical ventilation.These patients were randomized into two groups:one group used low tidal volume (6～8 mL/kg),while the other group used conventional tidal volume (10～12 mL/kg).Observe the changes of artery blood gas analysis after ventilation,time of mechanical ventilation and mortality.Follow up the respiratory system symptoms of survival patients.Results After 24 hours of mechanical ventilation,the PaO2 and P/F in conventional tidal volume group were higher than in low tidal volume group;PaCO2 and pH in conventional tidal volume group were lower than in low tidal volume group.The duration of mechanical ventilation in conventional tidal volume group was (5.4±1.8)d,while in low tidal volume group it was (9.5±1.7)d.The mortality of conventional tidal volume group was 16%,while in low tidal volume group it was 36%.Morbidity of survival patients with recurrent respiratory tract infection in conventional tidal volume group was 28.6%,while in low tidal volume group it was 31.3%.Conclusion Therapeutic effect of mechanical ventilation with conventional tidal volume is better than low tidal volume in the children with severe pneumonia.