Study on the Clinical Effect of Biofeedback Therapy for Functional Constipation

Objective:To assess the clinic effect of biofeedback therapy for functional constipation.Methods:Sixty cases of chronic functional constipation were randomly divided into treatment group (30 cases) and control group (30 cases).Cases in the treatment group were exposed to biofeedback for a five-week-long treatment course—individual treatment lasted for 30-45 minutes and twice per week.Patients in the control group received PEG 4000 10g BID for five weeks.Data from constipation symptom score,colonic transit test,and anorectal manometry were done and compared before and after two kinds of treatments.Results:Biofeedback training and PEG 4000 could restore the stoolfrequency,stool characteristics and accompanying symptoms to normal or mitigation of the majority of patients with chronic functional constipation,with the total effective rates being 66.7% and 80% (P0.05),respectively.After biofeedback training and PGE 4000 treatment,the discharge rate of 72-hour markers of colonic transit test significantly increased to 75% and 73%,respectively.Additionally,anorectal pressure decreased dramatically after biofeedback training.Conclusion:Biofeedback training would play a positive role in outlet obstruction and slow transit constipation.Thus,it could be an effective first-line treatment of chronic functional constipation.