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Clinical Study about Treatment of Postmenopausal Osteoporosis with Guilu Yanggu Decoction

Jianhua Huang

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Abstract

Objective:To explore the effect of Guilu Yanggu Decoction on the patients with postmenopausal osteoporosis(PMOP)and its possible mechanism.Methods:120 patients of PMOP were randomly divided two groups.The treatment group were administered Guilu Yanggu Decoction while the control group were given Luogaiquan(10mg/d).A period of treatment was 6 months.The levels of BMD,BGP,E2 and IL-6 before and after treatment were observed.Results:After a year,the total effective rate in the treatment group was significantly higher than that in the control group,91.84% vs 73.21%(P0.01).And the treatment group was also significantly better than the control group in increasing BMD,BGP and E2(p0.05),and decreasing IL-6(P0.05).Conclusion:Guilu Yanggu Decoction can significantly improve the symptoms and increase the levels of BMD,BGP and E2.It is good for PMOP than Luogaiquan.It should be applied gererally.

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What this paper is about

Objective:To explore the effect of Guilu Yanggu Decoction on the patients with postmenopausal osteoporosis(PMOP)and its possible mechanism.Methods:120 patients of PMOP were randomly divided two groups.The treatment group were administered Guilu Yanggu Decoction while the control group were given Luogaiquan(10mg/d).A period of treatment was 6 months.The levels of BMD,BGP,E2 and IL-6 before and after treatment were observed.Results:After a year,the total effective rate in the treatment group was significantly higher than that in the control group,91.84% vs 73.21%(P0.01).And the treatment group was also significantly better than the control group in increasing BMD,BGP and E2(p0.05),and decreasing IL-6(P0.05).Conclusion:Guilu Yanggu Decoction can significantly improve the symptoms and increase the levels of BMD,BGP and E2.It is good for PMOP than Luogaiquan.It should be applied gererally.

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Available abstract

Objective:To explore the effect of Guilu Yanggu Decoction on the patients with postmenopausal osteoporosis(PMOP)and its possible mechanism.Methods:120 patients of PMOP were randomly divided two groups.The treatment group were administered Guilu Yanggu Decoction while the control group were given Luogaiquan(10mg/d).A period of treatment was 6 months.The levels of BMD,BGP,E2 and IL-6 before and after treatment were observed.Results:After a year,the total effective rate in the treatment group was significantly higher than that in the control group,91.84% vs 73.21%(P0.01).And the treatment group was also significantly better than the control group in increasing BMD,BGP and E2(p0.05),and decreasing IL-6(P0.05).Conclusion:Guilu Yanggu Decoction can significantly improve the symptoms and increase the levels of BMD,BGP and E2.It is good for PMOP than Luogaiquan.It should be applied gererally.

Key concepts: Decoction, Medicine, Postmenopausal osteoporosis, Osteoporosis, Internal medicine, Postmenopausal women, Bone mineral

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