Detection of mycoplasma from female urogenital tract and drug susceptibility analysis

OBJECTIVE To provide experimental basis for clinic treatment and guide proper application of medicine in clinic by analysing the mycoplasma infection and the drug-resistance to antibiotics in female patients in the clinic of gynaecology center and in-patient department.METHODS With broth method,to cultivate,identify and had a drug sensitivity test on Ureaplasma urealyticum(Uu) and Mycoplasma hominis(Mh) in the 522 female patients who had urogenital tract infection.RESULTS In the 522 samples,the positive rate of Mycoplasma infection was 48.3%,of which the Uu was 36.6%,the Uu with Mh is 11.3% and the Mh only is 0.4%.To josamycine,minocycline and doxycycline,the drug resistance rates of Mycoplasma was lower,but to tetracycline,erythromycin,ofloxacin and norfloxacin those was higher.There was a obviously higher drug resistance rate in patients with Uu and Mh mixed infection than those with Uu infection only.CONCLUSION Mycoplasma,which has had multi-drug resistant strains,is a kind of important pathogenic bacteria in the female urogenital tract infection.Therefore timely and effective drug sensitivity tests not only have great significance to grasping the prevalence and drug resistance degree of mycoplasma,but also provide significant basis for properly chosing clinical antibiotics.