The relationship between abnormal circadian rhythm of blood pressure and left ventricular hypertrophy in patients with hypertension

Objective: To observe the relationship between abnormal circadian rhythm of blood pressure and left ventricular hypertrophy in patients with hypertension. Methods: Used ambulatory blood pressure to monitor the blood pressure in 134 patients with primary hypertension,left ventricular hypertrophy was measured by cardiac ultra-evaluation. Results: In 134 patients with hypertension,13 patients with non-dipper blood pressure(9.7%). Blood pressure rhythm abnormalities had no relationship with gender,age,BMI(P0.05), but related with ventricular weight index (t=7.913,P=0.000). The incidence of left ventricular hypertrophy in non-dipper blood pressure group was 69.2%,higher than that of 18.2% in the dipper blood pressure group (χ2=17.203,P=0.000), The OR value 10.125, 95% CI of 2.488-48.010. Logistic regression analysis showed that blood pressure rhythm abnormalities, hypertension severity, blood pressure controls and pulse pressure were the indepen-dent risk factor for left ventricular hypertrophy in patients with essential hypertension. Conclusion: The circadian rhythm abnormalities of patients with hypertension are easy to complicate with left ventricular hypertrophy. Therefore, in the treat-ment of hypertension, we must also regulate the normal physiological of blood pressure rhythm.