Retrospetive Review of 32 Patients with Malignant Biliary Obstruction Treated by Endoscopic Retrograde Biliary Drainage

Objective To explore the clinical effects of biliary tract endoprosthesis through endoscopic retrograde cholangiopan creatography(ERCP) on unresectable malignant biliary obstruction(MBO).Methods A retrospective review of 32 patients with malignant obstructive jaundice receiving ERCP was taken.Different biliary stents were placed according to the patient's conditions.Outcomes were followed at three and six months.Results ERCP were successful in 30 cases of all the 32 cases,the successful rate was 93.8%(30/32);and 18 cases were successfully embedded with self-expandable metal stents,12 cases were embedded with plastic stents;two cases had complications,the complications included ERCP associated pancreatitis(1 cases,3.33%) and cholangitis(1 cases,3.33%),but none of them had sequela after correct treatment.After stent was implanted,icteric and itch of skin were relieved quickly in 30 patients with malignant biliary obstruction.The serum level of total bilirubin decreased from(170.84±101.72) μmol/L to(105.42±82.44) μmol/L after treatment(P0.01).The follow-up in 21 patients(70%) indicated that the survival rates of 3 months and 6 months after the treatment were 93% and 79%,respectively.Conclusion Biliary stenting is effective and safe in the treatment of MBO patients with contraindications for surgical treatments.It is a good choice to improve symptoms and increase quality of life for the late MBO cases.