2008Wuhan Daxue xuebao. Yixue banRequires access

Analysis of 58 Cases of Malignant Biliary Obstruction Treated by Endoscopic Biliary Stent Insertion

Sun Quan

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Abstract

Objective: To investigate the clinical value and therapeutic effect of ENBD,EBMSD and ERBD via encoscopic retrograde cholangio-pancreatography(ERCP) on malignant obstructive jaundice.Methods: A retrospective review of 58 patients with malignant obstructive jaundice(37 men and 21 women with an average age of 61 years old) receiving ERCP.Different biliary stents or ENBD were placed according to the patient's conditions.Outcomes were followed after three and six months.Results: ERCP were successful in 56 cases of all the 58 cases,and 36 were successfully embedded with self-expandable metal stents,18 cases were embedded with plastic stents.The other two cases were only treated with ENBD.Five cases had complications,but none of them had sequela after correct treament.The serum level of total bilirubin decreased from(377.4±155.5)μmol/L to(146.4±54.5)μmol/L after treatment(P0.01).The follow-up investigation in 40 patients(70%) indicated that the survival rates of 3 months and 6 months after the treatment were 94% and 77% respectively.Conclusion: These results indicate that biliary stent insertion and ENBD via ERCP is an effective and safe palliative treatment for malignant bile duct obstruction.

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What this paper is about

Objective: To investigate the clinical value and therapeutic effect of ENBD,EBMSD and ERBD via encoscopic retrograde cholangio-pancreatography(ERCP) on malignant obstructive jaundice.Methods: A retrospective review of 58 patients with malignant obstructive jaundice(37 men and 21 women with an average age of 61 years old) receiving ERCP.Different biliary stents or ENBD were placed according to the patient's conditions.Outcomes were followed after three and six months.Results: ERCP were successful in 56 cases of all the 58 cases,and 36 were successfully embedded with self-expandable metal stents,18 cases were embedded with plastic stents.The other two cases were only treated with ENBD.Five cases had complications,but none of them had sequela after correct treament.The serum level of total bilirubin decreased from(377.4±155.5)μmol/L to(146.4±54.5)μmol/L after treatment(P0.01).The follow-up investigation in 40 patients(70%) indicated that the survival rates of 3 months and 6 months after the treatment were 94% and 77% respectively.Conclusion: These results indicate that biliary stent insertion and ENBD via ERCP is an effective and safe palliative treatment for malignant bile duct obstruction.

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Available abstract

Objective: To investigate the clinical value and therapeutic effect of ENBD,EBMSD and ERBD via encoscopic retrograde cholangio-pancreatography(ERCP) on malignant obstructive jaundice.Methods: A retrospective review of 58 patients with malignant obstructive jaundice(37 men and 21 women with an average age of 61 years old) receiving ERCP.Different biliary stents or ENBD were placed according to the patient's conditions.Outcomes were followed after three and six months.Results: ERCP were successful in 56 cases of all the 58 cases,and 36 were successfully embedded with self-expandable metal stents,18 cases were embedded with plastic stents.The other two cases were only treated with ENBD.Five cases had complications,but none of them had sequela after correct treament.The serum level of total bilirubin decreased from(377.4±155.5)μmol/L to(146.4±54.5)μmol/L after treatment(P0.01).The follow-up investigation in 40 patients(70%) indicated that the survival rates of 3 months and 6 months after the treatment were 94% and 77% respectively.Conclusion: These results indicate that biliary stent insertion and ENBD via ERCP is an effective and safe palliative treatment for malignant bile duct obstruction.

Key concepts: Medicine, Obstructive jaundice, Biliary stent, Jaundice, Stent, Bile duct, Surgery, Sequela

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Analysis of 58 Cases of Malignant Biliary Obstruction Treated by Endoscopic Biliary Stent Insertion — Research Paper | ScholarLens