Radiofrequency catheter ablation for nonsustained ventricular tachycardia and frequent ventricular premature contractions from left and right ventricular outflow tract

Objective To observe the results of radiofrequency catheter ablation for nonsustained ventricular tachycardia (N SuVT) and frequent premature ventricular contractions (PVCs) originating from left and right ventricular outflow tract, and also to evaluate the feasibility and safety of radiofrequency catheter ablation for eradication of symptomatic monomorphic ventricular ectopic beats and nonsustained ventricular tachycardia. Methods This study included 60 patients (M/ F,38/ 22),mean age (46.2±7.1)years.The site of origin was determined by activation mapping for the earliest endocardial activation ,and/ or by pace mapping for the exact QRS match between pacing and ectopic beat or N SuVT.Radiofrequency catheter ablation successed in 96.6%(58/60) patients with a mean frequency of ventricular ectopic beats of (122±140) after the ablation,P 0. 001. No complications encountered. During a mean followup period of (19±6) months ,the patient with successful ablation were not given any antiarrhythmic drugs and were symptom free in most of them. Results Recurrence occurred in 2 patients in the 58 successful cases ,and there were no late complications.In all patients,both N SuVT and PVCs shared the same electrocardiographic morphology, N SuVT and PVCs originating from left ventricular outflow tract with typical right bundle branch block and right ventricular outflow tract with typical left bundle branch block. 12 lead pacemapping demonstrated concordance with the N SuVT in 11 to 12 ECG leads.. During a follow up period of (13±6)months,N SuVT and PVCs recurred only in two patient. Conclusion Radiofrequency catheter ablation is a safe and effective treatment for patients with nonsustained ventricular tachycardia and frequent premature ventricular contractions originating from ventricular outflow tract. Appropriate selection of patients is very important.