Evaluation of Radiofrequency Catheter Ablation of Frequent Monomorphic Ventricular Ectopic Beats.

To evaluate the feasibility and safety of radiofrequency catheter ablation for eradication of symptomatic monomorphic ventricular ectopic beats.This study included 97 patients (M/F 38/59,mean age 46.2±7.1 years;right ventricular outflow tract oringin in 95 patients and left ventricular outflow tract oringin in 2 patients ) with severely symptomatic frequent ventricular ectopic beats (mean frequency 20416±1891/24 hours).The site of origin was determined by activation mapping for the earliest endocardial activation,and/or by pace mapping for the exact QRS match between pacing and ectopic beat.Radiofrequency catheter ablation successed in 95.9%(93/97) patients with a mean frequency of ventricular ectopic beats of 122±140/24hours after the ablation, P 0.001.No complications encountered.During a mean follow up period of 19±6 months,the patient with successful ablation were not given any antiarrhythmic drugs and were symptom free in most of them (91.4%) .Recurrence occurred in 4 patients in the 93 successful cases,and there were no late complications.Conclusion:Radiofrequency catheter ablation is an effective and safe treatment for frequent monomorphic ventricular ectopic beats.It may therefore be a reasonable alternative for the treatment of severely symptomatic,drug resistant or intolerable monomorphic ventricular ectopic activities in patients without significant structural heart disease.