The High-dose Methylprednisolone Treatment in Acute Respiratory Distress Syndrome

Objective To investigate the time that start high-dose methylprednisolone treatment in acute respiratory distress syndrome(ARDS).Methods The clinic dates were collected from the ARDS patients who met the study requirements from 2008 to 2011.The patients in control group were given the ordinary ARDS treatments and the experimental group was given an additional treatment of high-dose Methylprednisolone.Results 28 patients(control group 16,experimental group 12) were diagnosed to be advanced stage ARDS according to their lung compliance,ect.After all treatments,the experimental group recovered faster than the control group,but there were no difference between the mortality.The infection induced death was higher in the experimental group.There were significant differences between the survivors and nonsurvivors of the experimental group in age,etc.Conclusion The lung compliance,ect.may be used to evaluate the time that start high-dose methylprednisolone treatment of ARDS.The age,basic stage of illness,ect.may predict the curative effect.