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HPLC Determination of Transfer Rate of Chlorgenic Acid in Flos Lonicerae Japonicae

Yu-ling Xu

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Abstract

OBJECTIVE To establish examination methods for detecting effective components of medicinal materials by observing the rate of chlorgenic acid in Flos Lonicerae Japonicae;to perfect the available quality standards of Flos Lonicerae Japonicae so as to establish the internal control quality standards of Flos Lonicerae Japonicae.METHOD Observations were made on the rate of chlorgenic acid in different batches of Flos Lonicerae Japonicae,using the same extraction method,followed by an analysis of the results.RESULT Different batches of the medicinal herb showed different rate although the extraction method was the same,which is likely to cause failure to meet the quality standards.CONCLUSION The authors suggest that it is advisable to add the examination item transfer rate of effective component,so as to better control the quality of the medicinal materials and ensure the quality of the patent Chinese medicine with Flos Lonicerae Japonicae as one of the ingredients.

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OBJECTIVE To establish examination methods for detecting effective components of medicinal materials by observing the rate of chlorgenic acid in Flos Lonicerae Japonicae;to perfect the available quality standards of Flos Lonicerae Japonicae so as to establish the internal control quality standards of Flos Lonicerae Japonicae.METHOD Observations were made on the rate of chlorgenic acid in different batches of Flos Lonicerae Japonicae,using the same extraction method,followed by an analysis of the results.RESULT Different batches of the medicinal herb showed different rate although the extraction method was the same,which is likely to cause failure to meet the quality standards.CONCLUSION The authors suggest that it is advisable to add the examination item transfer rate of effective component,so as to better control the quality of the medicinal materials and ensure the quality of the patent Chinese medicine with Flos Lonicerae Japonicae as one of the ingredients.

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Available abstract

OBJECTIVE To establish examination methods for detecting effective components of medicinal materials by observing the rate of chlorgenic acid in Flos Lonicerae Japonicae;to perfect the available quality standards of Flos Lonicerae Japonicae so as to establish the internal control quality standards of Flos Lonicerae Japonicae.METHOD Observations were made on the rate of chlorgenic acid in different batches of Flos Lonicerae Japonicae,using the same extraction method,followed by an analysis of the results.RESULT Different batches of the medicinal herb showed different rate although the extraction method was the same,which is likely to cause failure to meet the quality standards.CONCLUSION The authors suggest that it is advisable to add the examination item transfer rate of effective component,so as to better control the quality of the medicinal materials and ensure the quality of the patent Chinese medicine with Flos Lonicerae Japonicae as one of the ingredients.

Key concepts: Flos, Traditional medicine, Medicinal herbs, Chromatography, Chemistry, Medicine, Biochemistry, Rutin

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