The biological role of FasL expressing Hep G2 cells
Da Zhang
Abstract
Da Zhang
Abstract
Objective:To observe the biological role of FasL expressing hepatocytes.Methods:In order to investigate whether FasL exˉpressing HepG2x cells induce apoptosis of Fas expressing cells,apoptosis of Jurkat cells or HepG2cells was estimated by DNA fragmention on gel electrophesis or FACS when those cells cocultured with HepG2x cells for48hours.Results:FasL expression HepG2cells could induce apoptosis of Fas expressing HepG2cells or Jurkat cells.
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Objective:To observe the biological role of FasL expressing hepatocytes.Methods:In order to investigate whether FasL exˉpressing HepG2x cells induce apoptosis of Fas expressing cells,apoptosis of Jurkat cells or HepG2cells was estimated by DNA fragmention on gel electrophesis or FACS when those cells cocultured with HepG2x cells for48hours.Results:FasL expression HepG2cells could induce apoptosis of Fas expressing HepG2cells or Jurkat cells.
Key concepts: Jurkat cells, Fas ligand, Apoptosis, Cell biology, Medicine, Molecular biology, Immunology, Cancer research