Combination of transcatheter arterial chemoembolization and cool-tip radiofrenquency ablation in treating primary hepatocellular carcinoma

Objective To evaluate the clinical efficacy of transcatheter arterial chemoembolization(TACE) combined with cool-tip radiofrequency ablation(RFA) in treating moderate and primary hepatocellular carcinomas. Methods 65 cases of primary hepatocellular carcinoma were divided into two groups.31 cases were treated with TACE(group A).34 cases were treated with TACE and RFA(group B),including 35 tumors of these cases treated with cool-tip RFA.The evaluation of the therapeutic effects was carried out through DSA,CT,B-ultrasound and AFP. Results The complete necrosis rate of tumor,the recurrence rate,and one-year survival rate were 16.1%,48.4%,48.4% in group A,and 7.1%,17.7%,79.4% in groups B respectively.There were significant statistical differences between the two groups(P0.01).The rates of reduction in tumor diameter and the decline in serum AFP level in group A were 22.6%,19.4%,while those of group B were 32.4%,44.1%,respectively;with rigmificanit dififferences between the two groups(P0.05). Conclusions The therapeutic effects of TACE combined with cool-tip RFA show better results than that of TACE alone in treating the moderate and advanced stage primary hepatocelluation carcinoma with effecitive and reliable results,worthy to be necommanded.