Pathogens and drug resistance study of urinary tract infection in elderly patients

Objective To study pathogens and drug resistance of urinary tract infection in elderly patients,in order to choose right antibiotics for clinical treatment.Methods Bacterial culture and susceptibility test were carried out among 428 urine samples from elderly patients.Results Among 435 isolated strains,61.8% gram negative bacilli,25.1% gram positive bacilli and 10.3% fungi were detected.The positive rate of gram negative bacillus in elderly female patients was significantly higher than that in male patients(P0.01).Escherichia coli(39.1%) and Enterococcus spp(16.3%) were the most commom pathogens in gram negative bacilli and gram positive bacilli respectively.The effective agents against Escherichia coli producing extended spectrum β-lactamase(ESBLs) were imipenem,piperacilin-tazobactam,nitrofurantoin,ampicilin-sulbactam and amikacin.Vancomycin and linezolid showed 100% sensitive to Enterococcus spp.Methicillin resistant staphylococci strains were 90.6%.Conclusions Gram negative bacilli were the main pathogen for urinary tract infections in elderly patients.Bacterial susceptibility test showes important significance for clinical right antibiotics selection.