THE PATHOLOGICAL CHANGES IN SPONTANEOUS HEALING PROCESS OF BILIARY TRACT ELECTRICAL BURNS

Objective To investigate certain period of time,certain parts,and certain intensity of electric coagulation caused bile duct burns by ordinary light microscope,including the extent and scope of damage,the pathological process of self-repair.This animal experiments provide some theoretical basis for the immediate repair of intraoperative bile duct electrical burns.Methods The 45 New Zealand white rabbits were randomly divided into 1 week,2 weeks,4 weeks,8 weeks group after cauterization and sham operation group.20W power high-frequency electric coagulation surgical unit worked 1s.Did HE staining of bile duct and then made observation and analysis.Results The inflammation phase of repair process occurred in the first week;The proliferative phase of repair process was from the 1st week to the 4th week;The remodeling phase of repair process was from the 4th week to 8th week.From the electrocautery point 2.5 mm,5 mm,7.5 mm,vary degrees of bile duct pathological changes occurred in all groups except normal group.Conclusion The actual damage range of electrical burns of extrahepatic bile duct is much larger than the naked eye found.Extrahepatic bile duct electrical burns self-repair process is much slower than normal wound healing process.The proliferation and differentiation of bile duct epithelial cell play a key role in self-repair of bile duct electrical burns.