Changes of Procalcitonin and C-reactive Protein for Children with Infectious Diseases

Objective To explore changes of procalcitonin and C-reactive protein in children with infectious diseases.Methods Total 196 cases of suspected infection in hospitalized children respectively procalcitonin and C-reactive protein,in accordance with the discharge diagnosis data were divided into groups bacterial infection,viral infection,non-infected group 3 groups for statistical analysis.We detected procalcitonin and C-reactive protein levels in serums for 196 cases children of suspected infection by semi-quantitative immunochromatography assay(PCT-Q),the immune nephelometry assay respectively.In accordance with the discharge diagnosis data were divided into groups bacterial infection,viral infection,non-infected group for statistical analysis.Results 80 patients are PCT-positive in bacterial infection group,for with a positive rate of 86.02%;non-infection group,positive for 2 cases,the positive rate of 5.26%.Comparing positive rates for the two groups,it was significant difference.P0.001(χ2=75.15).1 case was PCT-positive in,viral infection groups.the positive rate was 1.54%.Compare with the bacterial infection group,the difference was significant,P0.001(χ2=109.30).CRP-positive0.05(χ2=4.96),there are significant differences.11 cases were CRP-positive in bacterial infection,the positive rate was 28.94%.1 case was CRP-positive in non-infection group,the positive rate was 3.57%.Comparing positive rates for the two groups,P0.01(χ2=6.98).there are significant differences.Conclusion PCT in clinical early to CRP to assist in diagnosis of children infected with a certain reference value,but compared with the PCT,its detection rate and sensitivity were lower than the PCT.therapeutical effect and prognosis.To assist in diagnosis of children with infectious diseases,CRP have a certain reference value.But compared with the PCT,its detection rate and sensitivity were lower than the PCT.