Analysis of change of immune status of patients with lower respiratory tract infection of postoperative general anesthesia

OBJECTIVE To study the variation of immune status of patients with lower respiratory tract infection postoperative general anesthesia. METHODS A total of 32 patients with lower respiratory tract infection postoperative general anesthesia in our hospital from Jan 2010 to Jun 2011 were selected as research object(the observation group) and 32 patients without lower respiratory tract infection postoperative general anesthesia at the same time were selected as control group,then the peripheral blood lymphocyte subsets,IL-2 and immunoglobulin of two groups were analyzed and compared. RESULTS The CD3(57.45±5.09)%,CD4(31.88±4.48)%,CD4/CD8(1.20±0.14),CD19(7.78±3.75)%,IgM(0.92±0.19)g/L,IL-2(100.35±21.35)pg/ml,of observation group were lower than CD3(65.21±5.24)%,CD4(36.12±4.25)%,CD4/CD8(1.51±0.13),CD19(9.45±3.15)%,IgM(1.38±0.22)g/L,IL-2(150.36±21.86)pg/ml,of control group,CD8(1.20±0.14)%,IgA(1.85±0.19)g/L,IgG(12.33±1.18)g/L,of observation group were higher than CD8(27.13±3.32)%,IgA(0.96±0.14)g/L,IgG(9.23±1.20)g/L of control group,and the serious the disease was,the bigger the change range was,(P0.05).There were significant differences between the two groups. CONCLUSION The immune status of patients with lower respiratory tract infection postoperative general anesthesia is low,and there is bigger correction between the levels and severity of infection.