Role of Common Pulmonary Function Testing in Diagnosis and Treatment of Asthma in Children

Objective To investigate the changes in the large and small airway function in children with asthma and the time interval changes by comparing the lung function indexes pre and post regular treatment.To reveal the response of airway to bronchodilator and the reversibility of airway stenosis and obstruction in children with asthma in different ages by comparing the changes of lung function of asthmatic children pre and post inhaled bronchodilator.Methods Twenty-five children with asthma were measured with general pulmonary at acute stage,remission stage of 3 months,6 months and 1 year,the measured value and the estimated value of different stage were compared.Moreover,10 cases of them were received bronchodilation test respectively among acute attack period.Results The measured value of forced vital capacity(FVC),forced expiratory volume in one second(FEV1),forced expiratory volume in one second to forced vital capacity ratio(FEV 1.0%),peak expiratory flow(PEF),forced expiratory flow after 25%,50%,75%(FEF25,FEF50,FEF75),maximal midexpiratory flow(MMEF75/25)were lower than predicted value in acute stage,then recovered in remission stage,the large airway function index were recovered after 3 months′ therapy,and after treatment of 1 year or more,the small airway function were recoveried.Indicators of large airway function such as FEV1 and PEF,and indicators of small airway function of FEF50,FEF75,MMEF75/25 etc.were recorded after atomized.Conclusions There are dynamical changes of the lung function index during acute and remission stage,so pulmonary function testing has a good assessment in diagnosis,efficacy and disease in children with asthma.