Ge Min
Abstract
A calcium channel blocker,gallopamil hydrochloride,was synthesized from 2-(3,4,5-trimethoxyphenyl) acetonitrile and 2-(3,4-dimethoxyphenyl)-N-methylethylamine by nucleophilic substitution and salt forming reaction.The structure was characterized by 1H NMR and MS.
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A calcium channel blocker,gallopamil hydrochloride,was synthesized from 2-(3,4,5-trimethoxyphenyl) acetonitrile and 2-(3,4-dimethoxyphenyl)-N-methylethylamine by nucleophilic substitution and salt forming reaction.The structure was characterized by 1H NMR and MS.
Key concepts: Chemistry, Hydrochloride, Gallopamil, Combinatorial chemistry, Organic chemistry, Calcium, Nifedipine