Effect of Telmisartan on the Casual/Dynamic Blood Pressure in Patients with Mild to Moderate Essential Hypertension

Objective To study the effect of telmisartan on the casual as well as dynamic blood pressure in patients with mild to moderate essential hypertension. Methods After a week of wash-out period,43 outpatients with mild to moderate essential hypertension were given each 40 mg of telmisartan PO,q.d.for 8 weeks.At the termination of the 2nd,4th and 8th week of the treatment course,casual blood pressure was taken in the morning.24 h dynamic blood pressure was registered before and at the end of the treatment course. Results The overall effective rate of telmisartan in the treatment was 79.1%.After the treatment,the average blood pressure in the whole day,day time and night time as well as 4 h following the medication were all lowered significantly(P0.01),respectively.The trough/peak ratios of systolic blood pressure and diastolic blood pressure were 68.4% and 79.3%,respectively. Conclusion Telmisartan was shown to be very effective in the treatment of patients with mild to moderate essential hypertension,its effect lasting 24 hours.