Study of characteristics of ambulatory blood pressure in Telmisartan treated renal hypertension

[Objective] To evaluate the effect of telmisartan in mild and moderate renal hypertension by ambulatory blood pressure.[Methods] Eight-nine patients with mild to moderate renal hypertension were treated with 80 mg telmisartan once a day for 4 weeks.Twenty-four hour ambulatory blood pressure was monitored before and after telmisartan taken.Average blood pressure of 24 h,daytime,night-time,blood pressure load,blood pressure variability and circadian rhythm of blood pressure.[Results] After 4 weeks of telmisartan treatment,average SBP and DBP of 24 h,daytime,night-time,blood pressure load values,blood pressure variability were significant different from those in pre-treatment(P0.01).Night-time decline rate of SBP,DBP after treatment were statistically significant(P0.01 or 0.05) more than that before treatment [(10±9)% vs(2±8)% and(8±10)% vs(3±13)%].[Conclusion] Telmisartan in patients with mild to moderate renal hypertension is effective,smooth and can restore blood pressure circadian rhythm.