2011•Journal of Tianjin University of Traditional Chinese MedicineRequires access

Determination of ginsenoside Rg1 in Shunaoxin capsules by HPLC

Feng Han

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Abstract

[Objective] To establish a method for the content determination of ginsenoside Rg1 in Shunaoxin capsules.[Method] A simple HPLC method for determination of ginsenoside Rg1 was established.The determina tion was carried out taking column as the mobile phase of acetonirilewater(85:15) and detection wavelength was 203 nm.[Result] The ginsenoside Rg1 input sample size showed a good linear relationship at the range of 0.542 8~2.715 μg and the correlation coefficient was 0.999 8.The average recovery of the added sample was 97.24%.RSD was 1.43%.[Conclusion] The method is simple,accurate,reproducible and can be used for content determination of ginsenoside Rg1 in jiangzhi capsules.

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[Objective] To establish a method for the content determination of ginsenoside Rg1 in Shunaoxin capsules.[Method] A simple HPLC method for determination of ginsenoside Rg1 was established.The determina tion was carried out taking column as the mobile phase of acetonirilewater(85:15) and detection wavelength was 203 nm.[Result] The ginsenoside Rg1 input sample size showed a good linear relationship at the range of 0.542 8~2.715 μg and the correlation coefficient was 0.999 8.The average recovery of the added sample was 97.24%.RSD was 1.43%.[Conclusion] The method is simple,accurate,reproducible and can be used for content determination of ginsenoside Rg1 in jiangzhi capsules.

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Available abstract

[Objective] To establish a method for the content determination of ginsenoside Rg1 in Shunaoxin capsules.[Method] A simple HPLC method for determination of ginsenoside Rg1 was established.The determina tion was carried out taking column as the mobile phase of acetonirilewater(85:15) and detection wavelength was 203 nm.[Result] The ginsenoside Rg1 input sample size showed a good linear relationship at the range of 0.542 8~2.715 μg and the correlation coefficient was 0.999 8.The average recovery of the added sample was 97.24%.RSD was 1.43%.[Conclusion] The method is simple,accurate,reproducible and can be used for content determination of ginsenoside Rg1 in jiangzhi capsules.

Key concepts: Ginsenoside Rg1, Chromatography, Ginsenoside, Correlation coefficient, High-performance liquid chromatography, Linear relationship, Linear correlation, Linear range

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