Assessment of Hepatic Hemodynamics with Dynamic Computed Tomography in Endstage Liver Disease after Transplantation

Objective To assess values of hepatic perfusion after liver transplantation by dynamic helical computed tomography, and to explore changes in hepatic hemodynamics after liver transplantation by compare the result of control group.Materials and Methods Dyanmic computed tomography parameters were evaluated in 9 patients with liver transplantation for end stage liver disease and in 13 controls. Arterial, protal venous,total hepatic perfusion, the hepatic perfusion index (HPI) were calculated with the smoothing procedure. The examinations of study group were performed in 12～20 days after liver transplantation. Results Hepatic perfusion parameters of transplanted and control group assessed with dynamic computed tomography respectively, were as follows: arterial, (0.383±0.1754) ml·min -1·ml -1 and (0.2827±0.0971) ml·min -1·ml -1; portal venous, (1.5763±0.1754) ml·min -1·ml -1 and (1.1885±0.3899) ml·min -1·ml -1 ; total perfusion, (1.9594±0.5727) ml·min -1·ml -1 and (1.4712±0.4451) ml·min -1·ml -1; HPI 19.51% and 18.97%. The differences were significant for the portal venous and total hepatic perfusion after liver transplantation (P=0.044 and 0.036).Conclusion A high portal perfusion was present in early stage after transplantation in end stage liver disease. Hepatic arterial perfusion of transplanted patients is not significant difference with normal, but the deviation is existed due to varity in individuals.