2013•Zhongguo mianyixue zazhiRequires access

Expression of GRP78 in differentiated gastric cancer tissue

Xian Yu

Abstract

Objective:To study the expression of GRP78 in differentiated gastric cancer tissue.Methods: The expression of GRP78 in well differentiated gastric adenocarcinoma and moderately differentiated gastric adenocarcinoma and poorly differentiated gastric adenocarcinoma were detected by Western blot and immunohistochemistry.Results: Western blot and immunohistochemistry results showed that the expression of GRP78 with gastric cancer differentiation degree the inverse correlation.Conclusion: The expression levels of GRP78 are difference at the gastric cancer differentiation degree,but lack the feasibility as the gastric cancer cell differentiation degree determination norm for reference.

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Key concepts: Immunohistochemistry, Western blot, Cancer, Adenocarcinoma, Pathology, Cellular differentiation, Gastric adenocarcinoma, Medicine