2012•Journal of Clinical Medicine in PracticeRequires access
Changes and clinical significance of serum prealbumin and C-reactive protein in patients with acute exacerbation of chronic obstructive pulmonary disease
JU Jian-ping
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Abstract
Objective To investigate the changes of serum prealbumin(PA) and C-reactive protein(CRP) and their clinical significance in patients with acute exacerbation of chronic obstructive pulmonary disease(COPD) after treatment.Methods The levels of serum PA and CRP in 78 cases with acute exacerbation of COPD admitted to hospital before and after treatment were detected and analyzed.The changes of the controls were compared.Results The levels of serum PA of patients with acute exacerbation of COPD were significantly lower than those in remission,those both before and after treatment were lower than those in the controls.The levels of serum CRP increased significantly.There were significant differences.Conclusion Serum PA and CRP can be used to evaluate the severity of patients with acute exacerbation of COPD.