Analysis of recurrence of Dukes B colorectal cancer following radical surgery

Objective To investigate the clinicopathologic factors leading to recurrence of Dukes B (T_ 3-4 N_0M_0) colorectal cancer following radical surgery. Methods Clinicalpathological factors leading to recurrence in 265 cases with colorectal cancer at Dukes B treated with radical surgery from 1990 to 1999 were retrospectively analyzed by using univariate method. There were 220 cases without recurrence and 45 with recurrence. Results Univariate analysis showed that prognosis of colorectal cancer at Dukes B was significantly associated with site of tumor. Tumor recurrence and metastasis, especially local metastasis, could easily occur after surgery for rectal cancer. Yet, age, gender, symptom duration, gross findings, histological differentiation, tumor size and depth of bowel wall invasion were not associated with tumor recurrence. Conclusion Cases with rectal cancer at stage of Dukes B have additional risks for postoperative local recurrence.