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Observation of the Therapeutic Effect of Compound Glycyrrhizin Injection on Chronic Hepatitis B

Yan Ning

Open publisher page 2 citations

Abstract

OBJECTIVE:To observe the therapeutic effect of compound glycyrrhizin injection(CG)on chronic hepatitis B(CHB).METHODS:45 patients with CHB were randomly divided into trial group(21 cases)and control group(22 cases)who received CG and diammonium glycyrrhizinate injection(DG)respectively.The changes of clinical symptoms,signs,liver function parameters and adverse reactions were observed after 12-week treatment.RESULTS:There were no significant differences in improvements of total bilirubin,ALT and AST between 2 groups(P0.05),however,adverse reactions in trial group were obviously less than those in control group.CONCLUSION:CG is effecacious and safe in the treatment of CHB and other damage of liver and its clinical efficacy is better than that of DG.

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What this paper is about

OBJECTIVE:To observe the therapeutic effect of compound glycyrrhizin injection(CG)on chronic hepatitis B(CHB).METHODS:45 patients with CHB were randomly divided into trial group(21 cases)and control group(22 cases)who received CG and diammonium glycyrrhizinate injection(DG)respectively.The changes of clinical symptoms,signs,liver function parameters and adverse reactions were observed after 12-week treatment.RESULTS:There were no significant differences in improvements of total bilirubin,ALT and AST between 2 groups(P0.05),however,adverse reactions in trial group were obviously less than those in control group.CONCLUSION:CG is effecacious and safe in the treatment of CHB and other damage of liver and its clinical efficacy is better than that of DG.

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Available abstract

OBJECTIVE:To observe the therapeutic effect of compound glycyrrhizin injection(CG)on chronic hepatitis B(CHB).METHODS:45 patients with CHB were randomly divided into trial group(21 cases)and control group(22 cases)who received CG and diammonium glycyrrhizinate injection(DG)respectively.The changes of clinical symptoms,signs,liver function parameters and adverse reactions were observed after 12-week treatment.RESULTS:There were no significant differences in improvements of total bilirubin,ALT and AST between 2 groups(P0.05),however,adverse reactions in trial group were obviously less than those in control group.CONCLUSION:CG is effecacious and safe in the treatment of CHB and other damage of liver and its clinical efficacy is better than that of DG.

Key concepts: Glycyrrhizin, Medicine, Bilirubin, Adverse effect, Gastroenterology, Internal medicine, Chronic hepatitis, Therapeutic effect

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