Research Progress of Mycobacterium Tuberculosis Resistance to First-line Oral Anti-TB Drug Mechanisms and Detection Methods

TB has been a difficult problem of hazards to human health.With the use of Chemotherapy drugs in the 1990s,the TB 's cure rate of could be more than 95%,so that we saw the the cure of the disease,and for a time we thought tuberculosiscould be controlled.However,the current situation is not that optimistic,even in some parts of the world,the TB crisis.Now,mycobacterium tuberculosis to first-line oral anti-TB drug resistance is becoming increasingly serious,so that the chemotherapy have reduced efficiency.In this context,the authors proceed from reality,objective,scientific point of view,contained the resistance of tuberculosis,the mechanisms of resistance and the new progress of the rapid detection technologies.