2011Anhui Medical and Pharmaceutical JournalRequires access

Clinical study of mannitol combined ileus tube to treat adhesive intestinal obstruction

XU Ai-zhong

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Abstract

Aim To explore the effects of mannitol on adhesive intestinal obstruction by ileus tube.Methods A total of 40 Adhesive intestinal obstruction patients were randomly divided into control group and experimental group.Patients in the control group were treated with routine therapy including fasting,nutritional support,maintaining electrolyte and acid-base balance,using somatostatin and ileus tube decompression.Patients in the experimental group received mannitol based on routine therapy.Results Experimental group had a better outcome as compared with control group,including a quick recovery of flatus and stool[95% and 35.2±1.4 h vs 75% and 43.0±3.9 h](P0.05),decreased degree of abdominal circumference[15.0±1.5 cm vs 13.2±1.4cm](P0.05),the disappearing time of gas-liquid and hospitalization time was shorter than the control group[41.7±7.0 h and 8.9±1.3 d vs 53.3±9.2 h and 13.2±1.4 d](P0.05).The rate of transferring to operation in experimental group(5%)was significantly lower than that in the control group(25%).Conclusion Using mannitol by ileus tube plus routine treatment is an effective method to treat adhesive intestinal obstruction by significantly improving clinical symptoms,increasing non-surgical cure ativerate,decreasing the rate of transferring to operation and shorten hospital stay.

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Aim To explore the effects of mannitol on adhesive intestinal obstruction by ileus tube.Methods A total of 40 Adhesive intestinal obstruction patients were randomly divided into control group and experimental group.Patients in the control group were treated with routine therapy including fasting,nutritional support,maintaining electrolyte and acid-base balance,using somatostatin and ileus tube decompression.Patients in the experimental group received mannitol based on routine therapy.Results Experimental group had a better outcome as compared with control group,including a quick recovery of flatus and stool[95% and 35.2±1.4 h vs 75% and 43.0±3.9 h](P0.05),decreased degree of abdominal circumference[15.0±1.5 cm vs 13.2±1.4cm](P0.05),the disappearing time of gas-liquid and hospitalization time was shorter than the control group[41.7±7.0 h and 8.9±1.3 d vs 53.3±9.2 h and 13.2±1.4 d](P0.05).The rate of transferring to operation in experimental group(5%)was significantly lower than that in the control group(25%).Conclusion Using mannitol by ileus tube plus routine treatment is an effective method to treat adhesive intestinal obstruction by significantly improving clinical symptoms,increasing non-surgical cure ativerate,decreasing the rate of transferring to operation and shorten hospital stay.

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Available abstract

Aim To explore the effects of mannitol on adhesive intestinal obstruction by ileus tube.Methods A total of 40 Adhesive intestinal obstruction patients were randomly divided into control group and experimental group.Patients in the control group were treated with routine therapy including fasting,nutritional support,maintaining electrolyte and acid-base balance,using somatostatin and ileus tube decompression.Patients in the experimental group received mannitol based on routine therapy.Results Experimental group had a better outcome as compared with control group,including a quick recovery of flatus and stool[95% and 35.2±1.4 h vs 75% and 43.0±3.9 h](P0.05),decreased degree of abdominal circumference[15.0±1.5 cm vs 13.2±1.4cm](P0.05),the disappearing time of gas-liquid and hospitalization time was shorter than the control group[41.7±7.0 h and 8.9±1.3 d vs 53.3±9.2 h and 13.2±1.4 d](P0.05).The rate of transferring to operation in experimental group(5%)was significantly lower than that in the control group(25%).Conclusion Using mannitol by ileus tube plus routine treatment is an effective method to treat adhesive intestinal obstruction by significantly improving clinical symptoms,increasing non-surgical cure ativerate,decreasing the rate of transferring to operation and shorten hospital stay.

Key concepts: Medicine, Mannitol, Ileus, Surgery, Bowel obstruction, Decompression, Gastroenterology, Anesthesia

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