Analysis of influencing factors of positive sputum in new smear positive pulmonary tuberculosis 2 months after treatment

Objective To explore the risk factors of positive sputum in new smear positive pulmonary tuberculosis 2 months after treatment. Methods The sputum of 61 patients with new smear positive pulmonary tuberculosis was still positive 2 months after the treatment. Their clinical data were analyzed by setting survey forms. The different factors were tested by χ2test. Results There were significant difference in number of lesions in lung,lung field with empty,new sputum smear of bacteria,diabetes mellitus and rule medication in intensive phase(P 0. 05). These 5 factors were included in the multivariate logistic regression analysis,and brought into the regression equation after exclude confounding intervention factors. According to the risk factors(high OR value) the rank of 5 factors was irregular medication(18. 7),diabetes mellitus(6. 1),the amount of bacteria in new sputum smear(3), the number of lung field with empty(1. 9),and the number of lesions in lung(1. 7). Conclusion The risk factors of patients with new smear positive pulmonary tuberculosis still having positive sputum 2 months after the treatment mainly include irregular medication,diabetes,the amount of bacteria in new sputum smear,the number of lung field with empty,and the number of lesions in lung. Therefore,we should pay attention to the pulmonary tuberculosis patients with large range of lesions,empty and discharge of bacteria before clinical treatment,and especially pay attention to whether they are complicated with diabetes mellitus or not. Their liver should be protected positively,and their drug allergy should be detected early,in order to reduce the decreased efficacy caused by diabetes and intermittent withdrawal.