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Application of 0.75% ropivacaine for spinal anesthesia in children

Luo Pin

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Abstract

Objective To observe the effects of different doses of ropivacaine for spinal anesthesia, and compare with bupivacaine. Methods Sixty ASAI-Ⅱ children, scheduled for low abdominal surgery and lower limb operations were randomly allocated to three groups ,group A was received 0.75% ropivacaine 0.15mg/ spinal length, group B was received 0.75% ropivacaine 0.3mg/spinal length, group C was received 0.5% bupivacaine 0.15mg/ spinal length. The onset time and duration,the upper level of anesthesia, degree of motor block were recorded , the vital signs of the kids were recorded during the surgery. Results There were statistic differences in the upper level of anesthesia , duration time of T10 sensory block, the fixed time of sensory block, onset time of motor block and the motor recuperation time between group A and group C(F = 0.16,7.03,0.57,19.23,1.17 , P0.05), and group B (F =0.21,6.78,0.78,17.98,1.23, P0.05). The degree of the motor block of group A was weaker than group C(χ2= 40.83,21.16,10.42, P0.05), and group B(χ2= 36.01,21.16,9.60,P0.05). The motor recuperation time of group B was faster than group C(F=1.23,P0.05). There were no differences in onset time of sensory block between group B and the other 2 groups(F= 4.13,4.54, P0.05,).Conclusions 0.3mg/spinal length 0.75% ropivacaine is safe anesthesia for children; 0.15mg/ spinal length ropivacaine is a weaker motor block and sensory block than bupivacaine.

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What this paper is about

Objective To observe the effects of different doses of ropivacaine for spinal anesthesia, and compare with bupivacaine. Methods Sixty ASAI-Ⅱ children, scheduled for low abdominal surgery and lower limb operations were randomly allocated to three groups ,group A was received 0.75% ropivacaine 0.15mg/ spinal length, group B was received 0.75% ropivacaine 0.3mg/spinal length, group C was received 0.5% bupivacaine 0.15mg/ spinal length. The onset time and duration,the upper level of anesthesia, degree of motor block were recorded , the vital signs of the kids were recorded during the surgery. Results There were statistic differences in the upper level of anesthesia , duration time of T10 sensory block, the fixed time of sensory block, onset time of motor block and the motor recuperation time between group A and group C(F = 0.16,7.03,0.57,19.23,1.17 , P0.05), and group B (F =0.21,6.78,0.78,17.98,1.23, P0.05). The degree of the motor block of group A was weaker than group C(χ2= 40.83,21.16,10.42, P0.05), and group B(χ2= 36.01,21.16,9.60,P0.05). The motor recuperation time of group B was faster than group C(F=1.23,P0.05). There were no differences in onset time of sensory block between group B and the other 2 groups(F= 4.13,4.54, P0.05,).Conclusions 0.3mg/spinal length 0.75% ropivacaine is safe anesthesia for children; 0.15mg/ spinal length ropivacaine is a weaker motor block and sensory block than bupivacaine.

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Available abstract

Objective To observe the effects of different doses of ropivacaine for spinal anesthesia, and compare with bupivacaine. Methods Sixty ASAI-Ⅱ children, scheduled for low abdominal surgery and lower limb operations were randomly allocated to three groups ,group A was received 0.75% ropivacaine 0.15mg/ spinal length, group B was received 0.75% ropivacaine 0.3mg/spinal length, group C was received 0.5% bupivacaine 0.15mg/ spinal length. The onset time and duration,the upper level of anesthesia, degree of motor block were recorded , the vital signs of the kids were recorded during the surgery. Results There were statistic differences in the upper level of anesthesia , duration time of T10 sensory block, the fixed time of sensory block, onset time of motor block and the motor recuperation time between group A and group C(F = 0.16,7.03,0.57,19.23,1.17 , P0.05), and group B (F =0.21,6.78,0.78,17.98,1.23, P0.05). The degree of the motor block of group A was weaker than group C(χ2= 40.83,21.16,10.42, P0.05), and group B(χ2= 36.01,21.16,9.60,P0.05). The motor recuperation time of group B was faster than group C(F=1.23,P0.05). There were no differences in onset time of sensory block between group B and the other 2 groups(F= 4.13,4.54, P0.05,).Conclusions 0.3mg/spinal length 0.75% ropivacaine is safe anesthesia for children; 0.15mg/ spinal length ropivacaine is a weaker motor block and sensory block than bupivacaine.

Key concepts: Ropivacaine, Medicine, Anesthesia, Spinal anesthesia, Motor block, Block (permutation group theory), Bupivacaine, Group B

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