Research on regional cerebral blood flow in children with attention deficit or/and hyperactivity-impulsivity disorder
Jun Liu
Abstract
Jun Liu
Abstract
To understand the characteristic of regional cerebral blood flow (rCBF)of inattentive type and combined subtype of ADHD. rCBF was examined with single photon emission computed tomograghy in 40 children with ADHD and 11 healthy normal boys as controls. Qualitative analysis results showed that the rate of low rCBF was significantly higher in ADHD groups (57.5%)than that in controls(9%).The low rCBF brain zones included frontal lobe, temporal lobe, occipital lobe and thalamus, among which the highest rate was observed in frontal lobe. The rate of low rCBF was significantly higher in the combined subtype groups (66.7%)than that in the inattentive type groups(47.3%).At the same time, the low rCBF in the left brain zones of the combined subtype group was 14 cases,while in the right zones was 10 cases, showing significant difference between the brain zones of the two sides. [Conclusion] The results of the study suggest that the lower rCBF in frontal lobe links up with behavior disinhibition, meanwhile there is relation between the lower rCBF in left brain zones and the intensity of the state of ADHD.
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To understand the characteristic of regional cerebral blood flow (rCBF)of inattentive type and combined subtype of ADHD. rCBF was examined with single photon emission computed tomograghy in 40 children with ADHD and 11 healthy normal boys as controls. Qualitative analysis results showed that the rate of low rCBF was significantly higher in ADHD groups (57.5%)than that in controls(9%).The low rCBF brain zones included frontal lobe, temporal lobe, occipital lobe and thalamus, among which the highest rate was observed in frontal lobe. The rate of low rCBF was significantly higher in the combined subtype groups (66.7%)than that in the inattentive type groups(47.3%).At the same time, the low rCBF in the left brain zones of the combined subtype group was 14 cases,while in the right zones was 10 cases, showing significant difference between the brain zones of the two sides. [Conclusion] The results of the study suggest that the lower rCBF in frontal lobe links up with behavior disinhibition, meanwhile there is relation between the lower rCBF in left brain zones and the intensity of the state of ADHD.
Key concepts: Cerebral blood flow, Disinhibition, Frontal lobe, Psychology, Impulsivity, Thalamus, Occipital lobe, Attention deficit hyperactivity disorder