Preparation and Clinical Effect of Jianyinling Suppository

Objective:To develop Jianyinling suppository,check the quality and the stability, and observe its clinical effect.Methods:The active ingredients were extracted from the chinese traditional medicinal materials in prescription and mixed into the base of suppository to make into suppository.Then the quality targets such as pH,naphtha,absorbility,disintegration were tested,and the stability was checked through the way of factor test,acceleration test,sample observation.Its efficacy was observed in 103 patients with monilial vaginitis and the contrast was carried out between the treated group and the control group.Results:The quality and stability of the suppository we high under the temperature of 35℃ and the relative humidity of 75%. Total effective rate of 94.2% was obstained in the clinical trial.Conclusion: The fluconazole vaginal suppository can be prepared by a simple process and its content can be conveniently determined with accurate results,and the treated group has an obviously better effect than the control group. It is worthwhile to popularize and apply.