Clinical rescue experience of 42 cases of acute organophosphate poisoning

Objective To summarize the rescue method of acute organophosphate poisoning.Methods Forty-two cases of patients with organophosphate poisoning were pumped into atropine by the micro-pump continually.Strict observation was done before atropinization was completed in order to prevent excessive Atropine intake and atropine poisoning.Results Five out of 42 cases were reported dead and the remaining cases were improved and discharged after treatment.The total cure rate was 88.10%.The average atropinization time was(138.5±38.2) min,and atropinization process required(78.3±6.8) mg.Two cases(4.76%) had Atropine overdose and poisoning,3 cases(7.14%) condition rebounding,and 2 cases(4.76%) intermediate syndrome.Conclusion Using continuous micro-pump into the Atropine in acute organophosphate poisoning rescue can reduce the required dose of atropinization and reduce the risk of overdose and poisoning.