Levels and Correlated Factors of Serum Resistin in Patients with Hyperuricacidemia

Objective To analyze serum resistin levels and the correlated factors in patients with hyperuricacidemia.Methods Fasting serum levels of resistin,together with some other biochemical indices,were examined in 208 hyperuricacidemia(HUA) patients and 200 normouricemia(NUA) controls.Comparison between the two groups were carried out with the correlated factors of resistin levels analyzed.Results Systolic pressure,body mass index(BMI),waist circumference(WC),levels of fasting serum insulin(FINS),triacylglycerol(TG),and low density lipoprotein cholesterol,insulin resistance index,and fasting serum resistin levels were significantly higher in the HUA group than in the NAU group(P0.05).Postprandial blood sugar levels,diastolic pressure,levels of high density lipoprotein cholesterol and total cholesterol were not significantly different between the two groups(P0.05).Logistic regression analysis demonstrated that fasting plasma glucose(FPG),FINS,TG,BMI and WC were risk factors for fasting resistin level.Conclusion Fasting serum resistin levels are higher in the HUA population than in their NUA counterparts.Fasting resistin level is strongly correlated with FPG,FINS,TG,BMI and WC.