Experimental Study on Immediate Removal of Ligation of Common Bile Duct in Cholecystectomy

Objective To evaluate the injury of common bile duct in immediate removal of the ligation in cholecystectomy. Methods Eighteen healthy Japanese rabbits were selected and divided into three groups randomly: A group treated with simple cholecystectomy, B group with cholecystectomy plus common bile duct cross-ligation and C group with cholecystectomy plus hepatic bile duct conjunction “Y”-type ligation. The ligation was removed after 5 min in B and C groups. The levels of serum transaminase and bilirubin and pathological changes of bile duct and liver in each group were observed respectively. Results There were no statistic difference in the levels of GPT, GOT, total bilirubin (TB), direct bilirubin (DB) and DB/TB on 12 hours before operation and the 1st and 7th day after operation between A and ligation groups (P0.05). But there were statistic difference in the those indexes and pathological changes of bile duct and liver between A and ligation groups on the 30th and 90th day after operation (P0.05). Conclusion During cholecystectomy, immediate removal of common bile duct ligation doesn’t affect short-term results, but the long-term results are bile duct stricture and obstruction.