Comparison of the effect between painless and conventional electronic colonoscopy

Objective To compare the outcome of 2,200 patients underwent electronic colonoscopy, to investigate the local prevalence of lower gastrointestinal diseases, and to explore the feasibility and safety of painless colonoscopy. Methods The data of 2,200 patients who underwent electronic colonoscopy were analyzed retrospectively, and the positive rate of examination and the incidence of adverse reactions between painless colonoscopy (group A, n = 1,039) and conventional colonoscopy (group B, n = 1,161) were compared. In group A, midazolam ( 0.01 mg/kg), fentanyl (0.001 mg/kg), and propofol (1 ～ 1.5 mg/kg) were slowly intravenously administered before colonoscopy, and in group B, conventional methods of colonoscopy was performed. Specialist assessment of adverse reactions was recorded during and after operation. Results The positive rate of colonoscopy was 91.32%. There was no significant difference between two groups (P 0.05). The prevalence of disease spectrum was as follows: chronic colitis/proctitis, colon polyps, hemorrhoids, colorectal cancer, inflammatory bowel disease, colonic diverticula, vascular malformations and appendix stone. Serious adverse event was 0.14%.The HR, BP and SpO2 in group A and group B during and after operation was no difference (P 0.05). The rate of adverse event during colonoscopy in group A was lower than that in group B(P 0.001), and the success rate of colonoscopy in group A was higher than in group B (P 0.05). Operation time in group A was significantly shorter than that in group B(P 0.01). Conclusions In spite of the equal power in the positive rate of disease detection, painless electronic colonoscopy had a higher success rate, shorter operation time, and satisfactory feeling for both doctors and patients.