Species and antimicrobial resistance of coagulase-negative Staphylococcuscausing nosocomial infections

OBJECTIVE To analyze the species and antimicrobial resistance of coagulase-negative Staphylococcus(CNS) causing nosocomial infections and provide the scientific evidence for the reasonable use of antibiotics.METHODS Referring to National Guide to Clinical Laboratory Procedures,bacterial culture and identification were performed by routine methods.The drug susceptibility testing was performed using K-B method recommended by CLSI.RESULTS Among 167 strains of CNS,the detection rate of methicillin-susceptible coagulase-negative Staphylococcus(MSCNS) was 56.9%;the detection rate of methicillin-resistant coagulase-negative Staphylococcus(MRCNS) was 43.1%.The drug resistance rate of MRCNS to common antibiotics was obviously higher than that of MSCNS.100.0% of CNS were susceptible to glycopeptide antibiotics.CONCLUSION The clinicians should use the antibiotics specifically to postpone the increasing tendency of antimicrobial resistance and control the outbreak and prevalence of nosocomial infections.