2015•The Practical Journal of CancerRequires access

Risk Factors of 14V Lymph Node Metastasis in Gastric Carcinoma and Effect of Metastasis on the Prognosis

Ji Dong Lian

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Abstract

Objective To investigate the risk factors of 14 v lymph node metastasis in gastric carcinoma and effect of metastasis on the prognosis,and provide method to improve the prognosis of the patients. Methods Clinical data of 93 patients with gastric cancer treated with radical operation were retrospectively analyzed,and 14 v lymph node metastasis were observed and divided into metastasis group and non-metastasis group,the clinical data were compared between the 2 groups,factors affecting the prognosis were analyzed and prognosis were compared between the 2 groups. Results In 93 patients,there were 13 cases of 14 v lymph node metastasis,distant metastasis rate was 13. 98%. Single factor regression analysis showed that 2 groups of patients in the location of the lesion,tumor Borrmann type,lymph node metastasis and TNM staging was statistically significant( P 0. 05),in age,gender,tumor size,differentiation and infiltration depth difference was not statistically significant( P 0. 05); multi-factor regression analysis found that the lower part of the stomach,tumor,Borrmann type Ⅲ ~ Ⅳ type,lymph node metastasis in N3 and tumor TNM stage Ⅲ ~ Ⅳ were the independent risk factors for metastasis of gastric cancer 14 v lymph node( P 0. 05). Conclusion Patients with the above indexes has higher risk of 14 v lymph node metastasis,and all indexes should be clear before surgery to formulate corresponding lymph node dissection area. The lymph barrier function of patients can be effectively protected by remove the tumor,and ensure the prognosis and quality of life.

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Objective To investigate the risk factors of 14 v lymph node metastasis in gastric carcinoma and effect of metastasis on the prognosis,and provide method to improve the prognosis of the patients. Methods Clinical data of 93 patients with gastric cancer treated with radical operation were retrospectively analyzed,and 14 v lymph node metastasis were observed and divided into metastasis group and non-metastasis group,the clinical data were compared between the 2 groups,factors affecting the prognosis were analyzed and prognosis were compared between the 2 groups. Results In 93 patients,there were 13 cases of 14 v lymph node metastasis,distant metastasis rate was 13. 98%. Single factor regression analysis showed that 2 groups of patients in the location of the lesion,tumor Borrmann type,lymph node metastasis and TNM staging was statistically significant( P 0. 05),in age,gender,tumor size,differentiation and infiltration depth difference was not statistically significant( P 0. 05); multi-factor regression analysis found that the lower part of the stomach,tumor,Borrmann type Ⅲ ~ Ⅳ type,lymph node metastasis in N3 and tumor TNM stage Ⅲ ~ Ⅳ were the independent risk factors for metastasis of gastric cancer 14 v lymph node( P 0. 05). Conclusion Patients with the above indexes has higher risk of 14 v lymph node metastasis,and all indexes should be clear before surgery to formulate corresponding lymph node dissection area. The lymph barrier function of patients can be effectively protected by remove the tumor,and ensure the prognosis and quality of life.

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Available abstract

Objective To investigate the risk factors of 14 v lymph node metastasis in gastric carcinoma and effect of metastasis on the prognosis,and provide method to improve the prognosis of the patients. Methods Clinical data of 93 patients with gastric cancer treated with radical operation were retrospectively analyzed,and 14 v lymph node metastasis were observed and divided into metastasis group and non-metastasis group,the clinical data were compared between the 2 groups,factors affecting the prognosis were analyzed and prognosis were compared between the 2 groups. Results In 93 patients,there were 13 cases of 14 v lymph node metastasis,distant metastasis rate was 13. 98%. Single factor regression analysis showed that 2 groups of patients in the location of the lesion,tumor Borrmann type,lymph node metastasis and TNM staging was statistically significant( P 0. 05),in age,gender,tumor size,differentiation and infiltration depth difference was not statistically significant( P 0. 05); multi-factor regression analysis found that the lower part of the stomach,tumor,Borrmann type Ⅲ ~ Ⅳ type,lymph node metastasis in N3 and tumor TNM stage Ⅲ ~ Ⅳ were the independent risk factors for metastasis of gastric cancer 14 v lymph node( P 0. 05). Conclusion Patients with the above indexes has higher risk of 14 v lymph node metastasis,and all indexes should be clear before surgery to formulate corresponding lymph node dissection area. The lymph barrier function of patients can be effectively protected by remove the tumor,and ensure the prognosis and quality of life.

Key concepts: Medicine, Metastasis, Lymph, Gastric carcinoma, Lymph node, Oncology, Stage (stratigraphy), Lymph node metastasis

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