Risk Factors for Lymph Node Metastasis in Patients with Early Gastric Cancer

Objective To investigate the risk factors for lymph node metastasis in patients with early gastric cancer,and to explore the relationship between lymph node metastasis from early gastric cancer and clinical pathological factors.Methods According to intraoperative findings and postoperative pathological results,215 patients with early gastric cancer were divided into lymph node metastasis group(n=36)and non-metastasis group(n=179).Clinical and pathological data of patients were analyzed retrospectively.Results There were no significant differences in gender,age,tumor location,tumor type and differentiation degree between the two groups(P0.05).However,the differences in tumor invasion depth,maximum tumor diameter and Helicobacter pylori infection were obvious between the two groups(P0.05).Multivariable logistic regression analysis revealed that tumor invasion depth was correlated with lymph node metastasis in patients with early gastric cancer(OR=3.103,95%CI=1.495-6.609).Conclusion Tumor invasion depth is an independent risk factor for lymph node metastasis in patients with early gastric cancer.