Infection of Helicobacter pylori in gastric remnant after subtotal gastrectomy

Objective To investigate the relationship between gastric remnant after subtotal gastrectomy and infection of Helicobacter pylori(Hp).Methods A total of 682 patients with remnant stomach in Chongqing were subjected to gastroendoscopy and biopsy specimens were taken. Rapid urease test,PCR,histological study with Warthin-Starry staining and ELISA were used to detect Hp infection,and the results were subjected to epidemiological analysis.Results Hp infection was detected in 27.42% patients with remnant stomach.No correlation was found between Hp infection and age,sex and postoperative duration.The infection rate of Hp was significantly higher in those by Billroth Ⅰ reconstruction(40.07 %) than those by Billroth Ⅱ(17.37 %),and in those without bile reflux(33.53 %) than those with(7.98 %),in those undergoing operation due to peptic ulcer,stomach perforation and gastrorrhagia(47.88 %) than those due to gastric cancer(22.66 %),and in those with ulcer and cancer in remnant stomach than those with chronic gastritis of the remnant stomach and infection of the anastomotic inflammation.Conclusion The lesion of gastric remnant is closely associated with Hp infection,especially in gastric residual cancer.Early treatment is recommended for Hp infection to reduce gastric residual lesion and decrease carcinogenesis in gastric remnant.