Clinical application of homocysteine detection in patients with acute coronary syndrome

Objective To explore the change of serum homocysteine(Hcy) level in the patients with acute coronary syndromes(ACS) to provide the basis for early prevention and treatment of ACS.Methods Serum Hcy level in normal control group and the ACD group was detected for statistical analysis.Results The Hcy level in the acute myocardial infarction(AMI) group was higher than that in the unstable angina(UAP) group(P0.05).The Hcy level in the ACS group was higher than that in the control group(P0.01).In the normal control group(56 cases),only 1 case showed abnormal Hcy with the abnormal rate of 1.78%,while in the ACS group(60 cases),40 cases revealed abnormal Hcy with the abnormal rate of 66.7%.The abnormal rate in the ACS group was significantly higher than that in the normal control group(P0.01).Conclusion Serum Hcy level in ACS patients is significantly increased,serum Hcy level in AMI is much higher than that in UAP,indicating Hcy plays an important role in the pathogenesis of ACS.High Hcy level is one of high risk factors of ACS.