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2011•China Medical HeraldRequires access

Preparation of Meloxicam Ethosomes Gel

Xiaoping Liu

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Abstract

Objective: To prepare Meloxicam Ethosomes Gel.Methods: The optimum preparation process of Meloxicam Ethosomes Gel was selected with orthogonal design.The rate of envelopment was determined by HPLC method.The shape,grainsize and its distribution of Meloxicam Ethosomes Gel were evaluated based on the Gel.Results: The prepared Ethosomes Gel with high encapsulation efficiency(74.70%) had narrow size distribution.The number of mean grain size was 16.95 μm.The Gel was translucent and ropy which was valued at 2.17 mg/10 g for its average content.Conclusion: The Meloxicam Ethosomes Gel with preferable stability is prepared with a uncomplicated technology.It is valuable with application prospect.

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What this paper is about

Objective: To prepare Meloxicam Ethosomes Gel.Methods: The optimum preparation process of Meloxicam Ethosomes Gel was selected with orthogonal design.The rate of envelopment was determined by HPLC method.The shape,grainsize and its distribution of Meloxicam Ethosomes Gel were evaluated based on the Gel.Results: The prepared Ethosomes Gel with high encapsulation efficiency(74.70%) had narrow size distribution.The number of mean grain size was 16.95 μm.The Gel was translucent and ropy which was valued at 2.17 mg/10 g for its average content.Conclusion: The Meloxicam Ethosomes Gel with preferable stability is prepared with a uncomplicated technology.It is valuable with application prospect.

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Available abstract

Objective: To prepare Meloxicam Ethosomes Gel.Methods: The optimum preparation process of Meloxicam Ethosomes Gel was selected with orthogonal design.The rate of envelopment was determined by HPLC method.The shape,grainsize and its distribution of Meloxicam Ethosomes Gel were evaluated based on the Gel.Results: The prepared Ethosomes Gel with high encapsulation efficiency(74.70%) had narrow size distribution.The number of mean grain size was 16.95 μm.The Gel was translucent and ropy which was valued at 2.17 mg/10 g for its average content.Conclusion: The Meloxicam Ethosomes Gel with preferable stability is prepared with a uncomplicated technology.It is valuable with application prospect.

Key concepts: Meloxicam, Medicine, Chromatography, Pharmacology, Chemistry

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