The level and clinical significance of serum MAO,MDA and hs-CRP in patients with depression

Objective By means of measuring the level of serum monoamine oxidase,malondialdehyde and high -sensitivity C - reactive protein(Hs - CRP) in patients with depression,to explore the correlation with the onset of depression. Methods Serum levels of MAO,MDA and hs - CRP of the 42 patients with depression were measured with the chemical color-imetry, thiobarbituric acid method and scattering immunity turbidimetric method separately,Compared with 30 normal healthy personses.Results It was significant higher in the level of serum MAO[(32.24±2.32) U/ml],MDA[(3.63±0.75) nmol/ ml],hs-CRP[(5.05±0.92) mg/L]in patients with depression than the normal control group[MAO(21.26±1.96) U/ ml,MDA(3.16±0.82) nmol/ml,hs-CRP(1.88±0.81) mg/L].There was significant difference.Conclusion The level of serum MAO,MDA,hs - CRP in patients with depression are significantly higher.It is related with pathophysiology of depression.