2012•Central South PharmacyRequires access

Effect of sinomenine hydrochloride on cell proliferation of human breast cancer cell MCF-7

Chen Di-zhao

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Abstract

Objective To investigate the effect of sinomenine on the proliferation of human breast cancer cell MCF-7.Methods The proliferation of cells was detected by MTT.Results SIN,5-FUR,and SIN combining with 5-FUR inhibited the growth of human breast cancer cell MCF-7.The inhibition order was: SINSIN combining with 5-FUR5-FUR.Conclusion Sinomenine can inhibit the proliferation of human breast cancer cell.SIN alone has a better inhibition in breast cell growth than 5-FUR and SIN combining 5-FUR.

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What this paper is about

Objective To investigate the effect of sinomenine on the proliferation of human breast cancer cell MCF-7.Methods The proliferation of cells was detected by MTT.Results SIN,5-FUR,and SIN combining with 5-FUR inhibited the growth of human breast cancer cell MCF-7.The inhibition order was: SINSIN combining with 5-FUR5-FUR.Conclusion Sinomenine can inhibit the proliferation of human breast cancer cell.SIN alone has a better inhibition in breast cell growth than 5-FUR and SIN combining 5-FUR.

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Available abstract

Objective To investigate the effect of sinomenine on the proliferation of human breast cancer cell MCF-7.Methods The proliferation of cells was detected by MTT.Results SIN,5-FUR,and SIN combining with 5-FUR inhibited the growth of human breast cancer cell MCF-7.The inhibition order was: SINSIN combining with 5-FUR5-FUR.Conclusion Sinomenine can inhibit the proliferation of human breast cancer cell.SIN alone has a better inhibition in breast cell growth than 5-FUR and SIN combining 5-FUR.

Key concepts: Sinomenine, MCF-7, Cell growth, Human breast, Breast cancer, Cell, MTT assay, Cancer research

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