PALLIATIVE BILIARY DRAINAGE TREATMENT AND PROGNOSIS ANALYSIS OF ADVANCED MALIGNANT OBSTRUCTIVE JAUNDICE

Objective To compare effects of several kinds of Palliative biliary drainage treatments on prognosis of Advanced malignant obstructive jaundice.Methods Clinicopathological data of 218 patients with Advanced malignant obstructive jaundice treated at the AnHui province Hospital from 2005 to 2011 were retrospectively analyzed.Results The 218 were divided into Open surgical drainage group(n = 55) and Endoscopic drainage group(n = 136),PTCD drainage group(n = 27) according to different kinds of treatments.One week after drainage the levels of TBIL,DBIL and ALT of the patients undergoing treatment all decreased in comparison with those before the treatment(P 0.05).jaundice reduction effect become to stabilize until two weeks,and in each group over the same period of bilirubin showed no significant difference(P 0.05).The postoperative Statistics complications show the incidence of complications of endoscopic drainage group was significantly lower than the other two groups,the difference was statistically significant(P 0.05).The survival of patients for Endoscopic drainage not significantly different from that of the surgical resection group(P 0.05).but the survival of patients of the Endoscopic drainage group longer than the PTCD group(P 0.05).Conclusion There were no significant differences in reducing jaundice,improve liver function for different drainage methods.Open drainage group and endoscopic drainage group prolong survival better than the the PTCD drainage group,and consider the safety of endoscopic treatment Therefore,endoscopic treatment is palliative treatment of choice for patients with Advanced malignant obstructive jaundice.