ScholarLens Back to search
2004•The Chinese Journal of Modern Applied PharmacyRequires access

Determination of matrine in matrine and glucose injection HPLC

Jinfei Li

Open publisher page 0 citations

Abstract

OBJECTIVE To establish a method for the determination of matrine in matrine and glucose injection.METHOD A HPLC method was used. The chromatographic conditions were as follows: Prodigy ODS(3) column(150mm×4.6mm,5μm) was analytic column; a mixture of MeOH-H_2O-(C_2H_5)_3N(500∶500∶2v/v),adjusted with 0.5mol·L~(-1) H_3PO_4 to pH of 7.4～7.5 was used as mobile phase; detector wavelength was at 220nm.RESULTS The average recovery of matrine was 100.13%, RSD was (1.5)%(n=5).CONCLUSION The method is simple, rapid, accurate and suitable for the quality control of this drug.

About this research paper

What this paper is about

OBJECTIVE To establish a method for the determination of matrine in matrine and glucose injection.METHOD A HPLC method was used. The chromatographic conditions were as follows: Prodigy ODS(3) column(150mm×4.6mm,5μm) was analytic column; a mixture of MeOH-H_2O-(C_2H_5)_3N(500∶500∶2v/v),adjusted with 0.5mol·L~(-1) H_3PO_4 to pH of 7.4～7.5 was used as mobile phase; detector wavelength was at 220nm.RESULTS The average recovery of matrine was 100.13%, RSD was (1.5)%(n=5).CONCLUSION The method is simple, rapid, accurate and suitable for the quality control of this drug.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

OBJECTIVE To establish a method for the determination of matrine in matrine and glucose injection.METHOD A HPLC method was used. The chromatographic conditions were as follows: Prodigy ODS(3) column(150mm×4.6mm,5μm) was analytic column; a mixture of MeOH-H_2O-(C_2H_5)_3N(500∶500∶2v/v),adjusted with 0.5mol·L~(-1) H_3PO_4 to pH of 7.4～7.5 was used as mobile phase; detector wavelength was at 220nm.RESULTS The average recovery of matrine was 100.13%, RSD was (1.5)%(n=5).CONCLUSION The method is simple, rapid, accurate and suitable for the quality control of this drug.

Key concepts: Matrine, Chromatography, High-performance liquid chromatography, Chemistry

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Determination of matrine in matrine and glucose injection HPLC — Research Paper | ScholarLens