Effects of auto-corneal limbus stem cell transplantation combined with mitomycin ctreatment in the improved pterygium surgery
Diao Lu
Abstract
Diao Lu
Abstract
Objective To explore the clinical effect and safety of auto-corneal limbus stem cell transplantation combined with MMC in the treatment of improved pteryglum surgery.Methods 46 patients(50 eyes)with pterygium received improved pterygium excision operation.During the surgery,the entire pterygium was striped with comeal epithelium,bare sclera was exposed to 0.2g /L MMC for 2~3min,the eyes were given auto-corneal limbus stem cell transplantation.Results All the cases were followed up for average 12 mo.the pterygium recurrence appeared in two eyes and no serious complication were observed.Conclusion These findings suggest that in the pterygium improved surgey auto-corneal limbus stem cell transplantation combined with topical MMC can significantly decrease the recurrence rate of pterygium,and it is a convenient,safe and effecfive method.
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Objective To explore the clinical effect and safety of auto-corneal limbus stem cell transplantation combined with MMC in the treatment of improved pteryglum surgery.Methods 46 patients(50 eyes)with pterygium received improved pterygium excision operation.During the surgery,the entire pterygium was striped with comeal epithelium,bare sclera was exposed to 0.2g /L MMC for 2~3min,the eyes were given auto-corneal limbus stem cell transplantation.Results All the cases were followed up for average 12 mo.the pterygium recurrence appeared in two eyes and no serious complication were observed.Conclusion These findings suggest that in the pterygium improved surgey auto-corneal limbus stem cell transplantation combined with topical MMC can significantly decrease the recurrence rate of pterygium,and it is a convenient,safe and effecfive method.
Key concepts: Pterygium, Medicine, Mitomycin C, Sclera, Transplantation, Complication, Surgery, Ophthalmology