Study on clinical application of fully automatic hematology analyzer Sysmex xe-2100

The new hematology analyzer Sysmex xe-2100(TOA Medical Electronics,Kobe,Japan)has a novel,combined,white blood cell differential,echnology and a special reagent system to enumerate nucleated red blood cells.Performance evaluation f both technologies of the Sysmex xe-2100 according to the H20A protocol of the National Committee for Clinical and Laboratory standards.Five-part white blood cell differential counts on the xe-2100 revealed excellent correlation with the manual reference method for neutronphils,lymphocytes,and eosinophils(r=0.925,0.922,and 0.877,repectively)and good correlation for monocytes and basophils(r=0.756,and 0.763,respectively).The efficiency rates of flagging for the presence of≥1% abnormal white blood cells were 83%.The correlation of antomated and microscopic nucleated red blood cell counts was excellent(r=0.97).From the present evaluation and ur former experience with other types of Sysmex analyzers,we conclude that the new white blood cell differential technology of the xe-2100 represents a further development toward more efficient flagging of abnormal white blood cells.