2011•Zhongguo yaofangRequires access

Efficacy Observation of Topiramate in the Treatment of Various Types of Epilepsy

Zhou Shao-hong

Abstract

OBJECTIVE:To observe the topiramate monotherapy clinical efficacy and safety of various types of epilepsy.METHODS:A retrospective analysis in Jan.2007-Jan.2010 of 250 cases of epilepsy patients with topiramate monotherapy treatment was analyzed.The clinical efficacy and safety was statistics analysis.RESULTS:Complete control of seizures in 68 cases,accounting for 27.2%;64 cases were markedly improved(25.6%);56 cases were effective(22.4%),total efficiency was 75.2%.Memory loss(13.6%),weight loss(8.8%),nausea(7.2%),the language barrier(5.6%),ADRs of sleepiness(4.8%),dizziness(4.4%),low heat(3.2%),kidney stones(2.8%) were found in treatment.CONCLUSION:Topiramate monotherapy for epilepsy has significant effect,complete control rate,and low ADRs.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Topiramate, Epilepsy, Medicine, Nausea, Clinical efficacy, Anesthesia, Pediatrics, Internal medicine